A new marker
THE CONTEXT
For a long time, methods of early detection in case of exposure to asbestos, are sought because of the high risk of cancer after such exposure.
Osteopontin
A clinical study showed that the presence of serum levels of osteopontin, a glycoprotein involved in cell-matrix interactions, is an effective screening tool for pleural mesothelioma. In an essay published recently, the sensitivity of the method was confirmed. High levels of osteopontin were found in mesothelioma cases, whatever their histological type and including the forms at an early stage.
PRACTICE ...
Measurement of serum levels of osteopontin in patients with a history of exposure to asbestos could become a sensitive and specific tool for early detection of disease.
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